CTD

Comparative Toxicogenomics Database: The Comparative Toxicogenomics Database (CTD) elucidates molecular mechanisms by which environmental chemicals affect human disease. Chemical-gene/protein interactions and chemical- and gene-disease relationships are curated from the published literature, and integrated with diverse data (chemicals, genes/proteins, human diseases, references, vertebrate and invertebrate organisms, and the Gene Ontology) to facilitate environmental health research. The CTD locator points to those records that contain curated data.


DrugPortal

NLM Drug Information Portal: The NLM Drug Information Portal gives users a gateway to selected drug information from the U.S. National Library of Medicine and other key government agencies. At the top of the page are links to individual resources with potential drug information, including summaries tailored to various audiences. Resources include the NLM search systems useful in searching for a drug, NLM research resources, resources organized by audience and class, and other NIH and government resources such as FDA and CDC.


eChemPortal

OECD eChemPortal: A resource provided by the The Organisation for Economic Co-operation and Development (OECD. The eChemPortal provides free public access to information on properties of chemicals:

  • Physical Chemical Properties
  • Ecotoxicity
  • Environmental Fate and Behaviour
  • Toxicity

ChemPortal allows simultaneous searching of reports and datasets by chemical name and number and by chemical property. Direct links to collections of chemical hazard and risk information prepared for government chemical review programmes at national, regional and international levels are obtained. Classification results according to national/regional hazard classification schemes or to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) are provided when available. In addition, eChemPortal provides also exposure and use information on chemicals


EMIC

Env. Mutagen Info. Center: EMIC contains current and older references to chemical, biological, and physical agents that have been tested for genotoxic activity. The records include full bibliographic references, keywords, chemical names, and CAS Registry Numbers. The file is produced by the Oak Ridge National Laboratory in cooperation with the NLM and funded by the EPA and the NIEHS.


EINECS

EU Inv of Exist. Comm. Chem Sub: The European Inventory of Existing Commercial Chemical Substances (EINECS)at ESIS (European chemical Substances Information System). For further information about EINECS, contact: Office for Official Publications of the European Communities, 2 rue Mercier, L-2985 Luxembourg; Telephone: 011-352-49928 425 66 or 011-352-488-573.


EPA ACToR

EPA Aggregated Comp. Tox Resource: (Aggregated Computational Toxicology Resource). ACToR is EPA’s online warehouse of all publicly available chemical toxicity data and can be used to find all publicly available data about potential chemical risks to human health and the environment. ACToR aggregates data from over 500 public sources on over 500,000 environmental chemicals searchable by chemical name, other identifiers and by chemical structure.

The data warehouse:

  • Allows users to search and query data from other EPA chemical toxicity databases including:
  • ToxRefDB (30 years and $2 billion worth of animal toxicity studies).
  • ToxCastDB (data from screening 1,000 chemicals in over 500 high-throughput assays).
  • ExpoCastDB (consolidate and link human exposure and exposure factor data for chemical prioritization).
  • DSSTox (provides high quality chemical structures and annotations).

EPA CompTox

CompTox Dashboard: The interactive Chemical Safety for Sustainability CompTox Dashboard (the iCSS CompTox Dashboard) is a part of a suite of databases and web applications developed by the US Environmental Protection Agency’s Chemical Safety for Sustainability Research Program. These databases and apps support EPA’s computational toxicology research efforts to develop innovative methods to change how chemicals are currently evaluated for potential health risks.


EPA SRS

EPA Substance Registry System: The Substance Registry System (SRS) provides information on chemical substances and how they are represented in the Environmental Protection Agency (EPA) regulations and data systems. Developed in response to recommendations of the Chemical Data Standard Working Group, the SRS supports and conforms to EPA’s Chemical Identification Data Standard, which provides a uniform way of referring to chemical substances and is a basis for sharing chemical information across EPA data systems.


FDA SRS

FDA Substance Registration System: The overall purpose of the joint FDA/USP Substance Registration System (SRS) is to support health information technology initiatives by generating unique ingredient identifiers (UNIIs) for substances in drugs, biologics, foods, and devices. The UNII is a non- proprietary, free, unique, unambiguous, non semantic, alphanumeric identifier based on a substance’s molecular structure and/or descriptive information.

The procedures and management of the SRS is provided by the SRS Board. The SRS Board includes experts from both FDA and USP. The SRS operating procedures defined by the SRS Board are detailed in the SRS Manual.


Haz-Map

Occ. Exposure to Haz. Agents: Haz-Map is an occupational toxicologydatabase designed to link jobs to hazardous job tasks which are linked to occupational diseases and their symptoms. It is a relational database of chemicals, jobs and diseases. The Haz-Map Jobs table is based on the 1997 Standard Occupational Classification (SOC) system. The Industries table is based on the Standard Industrial Classification system. The Diseases table is based on the International Classification of Diseases (ICD-9). Information from textbooks, journal articles, and electronic databases (HSDB, ACGIH Documentation of TLVs, ATSDR Toxicological Profiles, NIOSHTIC, and others) was classified and summarized to create the database.


MeSH

Medical Subject Headings File: The National Library of Medicine’s controlled vocabulary thesaurus consisting of a set of chemical names, subject terms, and chemical or subject MeSH headings that are arranged in both an alphabetical and a heirarchical structure. ChemIDplus includes only the chemical names and chemical MeSH headings from this file. More data may be found at www.nlm.nih.gov/mesh.


NIAID ChemDB

NIAID Chemical Database: The ChemDB HIV, Opportunistic Infection and Tuberculosis Therapeutics Database is a tool developed by NIAID to compile and annotate preclinical data on compounds with potential therapeutic action against HIV/AIDS and related opportunistic infections. This database is continually updated with information extracted from published literature, including the structure and activity of compounds that have been tested against HIV, HIV enzymes or opportunistic pathogens.


NIST WebBook

NIST Chemistry WebBook: The NIST Chemistry WebBook provides users with easy access to chemical and physical property data for chemical species through the internet. The data provided in the site are from collections maintained by the NIST Standard Reference Data Program and outside contributors. Data in the WebBook system are organized by chemical species. The WebBook system allows users to search for chemical species by various means. Once the desired species has been identified, the system will display data for the species. If a Mass Spectrum is available, it is displayed by default.


PAFA

FDA Substances added to food: U.S. Food and Drug Administration (FDA), Center for Food Safety and Applied Nutrition. For more information about PAFA, call TIMS Group at (202) 418-3040.


PubChem

PubChem: PubChem contains the chemical structures of small organic molecules and information on their biological activities. It was developed by the National Library of Medicine of the US National Institutes of Health (NIH) to support the Molecular Libraries and Imaging component of the NIH Roadmap Initiative.

PubChem’s chemical structure database may be searched on the basis of descriptive terms, chemical properties, and structural similarity. When possible, PubChem’s chemical structure records are linked to other NCBI databases. These include the PubMed scientific literature database, for example, and NCBI’s protein 3D structure database. PubChem also contains the results of high-throughput biological screening experiments.


PubMed

Biomedical Citations From PubMed: PubMed, available via the NCBI Entrez retrieval system, was developed by the National Library of Medicine (NLM), located at the U.S. National Institutes of Health (NIH). Entrez is the text-based search and retrieval system used at NLM for services PubMed provides access to citations from biomedical literature. LinkOut provides access to full-text articles at journal Web sites and other related Web resources. The primary component of PubMed is MEDLINE. MEDLINE is the NLM’s premier bibliographic database that contains references to journal articles in the life sciences with a concentration on biomedicine. A distinctive feature of MEDLINE is that the records are indexed with NLM’s Medical Subject Headings (MeSH). The database contains citations from 1950 to the present, with some older material.


PubMed AIDS

AIDS Citations from PubMed: PubMed AIDS Subset: PubMed, available via the NCBI Entrez retrieval system, was developed by the National Library of Medicine (NLM), located at the U.S. National Institutes of Health (NIH). Entrez is the text-based search and retrieval system used at NLM for services PubMed provides access to citations from biomedical literature. LinkOut provides access to full-text articles at journal Web sites and other related Web resources. The primary component of PubMed is MEDLINE. MEDLINE is the NLM’s premier bibliographic database that contains references to journal articles in the life sciences with a concentration on biomedicine. A distinctive feature of MEDLINE is that the records are indexed with NLM’s Medical Subject Headings (MeSH). The database contains citations from 1950 to the present, with some older material.


PubMed Cancer

Cancer Citations from PubMed: PubMed Cancer Subset: PubMed, available via the NCBI Entrez retrieval system, was developed by the National Library of Medicine (NLM), located at the U.S. National Institutes of Health (NIH). Entrez is the text-based search and retrieval system used at NLM for services PubMed provides access to citations from biomedical literature. LinkOut provides access to full-text articles at journal Web sites and other related Web resources. The primary component of PubMed is MEDLINE. MEDLINE is the NLM’s premier bibliographic database that contains references to journal articles in the life sciences with a concentration on biomedicine. A distinctive feature of MEDLINE is that the records are indexed with NLM’s Medical Subject Headings (MeSH). The database contains citations from 1950 to the present, with some older material.


PubMed Central

Full text biomedical articles: PubMed Central is a free digital archive of biomedical and life sciences journal literature at the U.S. National Institutes of Health (NIH), developed and managed by NIH’s National Center for Biotechnology Information (NCBI) in the National Library of Medicine (NLM). With PubMed Central, NLM is taking the lead in preserving and maintaining unrestricted access to the electronic literature, just as it has done for decades with the printed biomedical literature. PubMed Central aims to fill the role of a world class library in the digital age. It is not a journal publisher. NLM believes that giving all users free and unrestricted access to the material in PubMed Central is the best way to ensure the durability and utility of the archive as technology changes over time.


PubMed Central Mob

Full text biomedical articles: PubMed Central is a free digital archive of biomedical and life sciences journal literature at the U.S. National Institutes of Health (NIH), developed and managed by NIH’s National Center for Biotechnology Information (NCBI) in the National Library of Medicine (NLM). With PubMed Central, NLM is taking the lead in preserving and maintaining unrestricted access to the electronic literature, just as it has done for decades with the printed biomedical literature. PubMed Central aims to fill the role of a world class library in the digital age. It is not a journal publisher. NLM believes that giving all users free and unrestricted access to the material in PubMed Central is the best way to ensure the durability and utility of the archive as technology changes over time.


PubMed Mob

Biomedical Citations From PubMed: PubMed, available via the NCBI Entrez retrieval system, was developed by the National Library of Medicine (NLM), located at the U.S. National Institutes of Health (NIH). Entrez is the text-based search and retrieval system used at NLM for services PubMed provides access to citations from biomedical literature. LinkOut provides access to full-text articles at journal Web sites and other related Web resources. The primary component of PubMed is MEDLINE. MEDLINE is the NLM’s premier bibliographic database that contains references to journal articles in the life sciences with a concentration on biomedicine. A distinctive feature of MEDLINE is that the records are indexed with NLM’s Medical Subject Headings (MeSH). The database contains citations from 1950 to the present, with some older material.


PubMed Toxicology

Toxicology Citations From PubMed: PubMed Toxicology Subset: PubMed, available via the NCBI Entrez retrieval system, was developed by the National Library of Medicine (NLM), located at the U.S. National Institutes of Health (NIH). Entrez is the text-based search and retrieval system used at NLM for services PubMed provides access to citations from biomedical literature. LinkOut provides access to full-text articles at journal Web sites and other related Web resources. The primary component of PubMed is MEDLINE. MEDLINE is the NLM’s premier bibliographic database that contains references to journal articles in the life sciences with a concentration on biomedicine. A distinctive feature of MEDLINE is that the records are indexed with NLM’s Medical Subject Headings (MeSH). The database contains citations from 1950 to the present, with some older material.


TOXLINE

NLM TOXLINE on TOXNET: The TOXLINE database containes citations to the toxicological literature that is available under the TOXNET system. It contains citations to:

Technical reports and research projects: NTIS, CRISP, TSCATS, and FEDRIP.

Special Journal and other research literature, DART, RISKLINE, and CIS Archival collection (no longer being updated on TOXLINE):
BIOSIS, IPA, EMIC, ETIC, ANEUPL, EPIDEM, HMTC, NIOSH, PESTAB, and PPBIB.

For more information on the TOXLINE components, please visit the NLM TOXLINE Fact Sheet.

Citations from the toxicology subset of PubMed is now available in TOXLINE, and answers will display this content also.


TOXLINE Mob

NLM TOXLINE on TOXNET: The TOXLINE database containes citations to the toxicological literature that is available under the TOXNET system. It contains citations to:

Technical reports and research projects: NTIS, CRISP, TSCATS, and FEDRIP.

Special Journal and other research literature, DART, RISKLINE, and CIS Archival collection (no longer being updated on TOXLINE):
BIOSIS, IPA, EMIC, ETIC, ANEUPL, EPIDEM, HMTC, NIOSH, PESTAB, and PPBIB.

For more information on the TOXLINE components, please visit the NLM TOXLINE Fact Sheet.

Citations from the toxicology subset of PubMed is now available in TOXLINE, and answers will display this content also.


TSCAINV

EPA Chem. Sub. Inventory: The EPA Chemical Substances Inventory is produced by the U. S. Environmental Protection Agency, Office of Toxic Substances, Washington, D. C. 20460. For further information, contact (202) 554-1404.


Wikipedia

WikipediA – The Free Enclopedia: Wikipedia is a Web-based free content encyclopedia that is openly edited and freely readable. It has 187 independent language editions sponsored by the non-profit Wikimedia Foundation. Entries on traditional encyclopedic topics exist alongside those on almanac, gazetteer and current events topics. Its goal is to create “a world in which every single person on the planet is given free access to the sum of all human knowledge.” “Wikipedia is one of the most popular reference sites on the Web, receiving around 50 million hits per day.