Lisinopril – Uses, Side Effects, Dosage & Interactions

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Generic Name: Lisinopril
Brands: Prinivil, Qbrelis, Zestril
Class: Angiotensin Converting Enzyme Inhibitor
Availability: Prescription Needed
Molecular Formula: C₂₁H₃₁N₃O₅
Substance UNII: E7199S1YWR

What is Lisinopril?

Lisinopril is an angiotensin converting enzyme (ACE) inhibitor that is used to treat hypertension (high blood pressure) in adults and pediatric patients 6 years of age and older, congestive heart failure (CHF) and treatment of acute myocardial infarction (MI) (heart attack).

What is Lisinopril Used for?

Lisinopril is used to lower blood pressure in individuals suffering from hypertension, CHF, and within 24 hours of a MI.

How Does Lisinopril Work?

Lisinopril works by inhibiting the ACE enzyme in humans and animals. ACE works to convert angiotension I to angiotension II. Angiotension II is a vasoconstrictor (substance that narrows blood vessels) that increases blood pressure and stimulates the release of aldosterone (a hormone). Further, this can cause an increase in serum potassium.

How Long Does it Take for Lisinopril to Work?

It takes approximately 7 hours to reach peak serum concentration (maximum amount of a drug found in the bloodstream after a dose and is the standard used in pharmacokinetics).

Do NOT Use Lisinopril If:

If you are or become pregnant
- ACE inhibitors use during the second and third trimesters have been associated with fetal and neonatal injury and death.
If you have ever had angioedema (swelling of the face, tongue, neck, etc) when taking lisinopril in the past

More about Lisinopril

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