OverviewDosageSide EffectsInteractionsHalf-Life

Abilify (aripiprazole) was the 112th most commonly prescribed drug in the United States in 2017. In that year alone, there were over 6.5 million prescriptions. Considering how popular this drug is right now, it pays to know a little bit more about this medication, including how long Abilify stays in your system.

Basic Information

Mean effective half-life: 75 hours  & IM ER formulation 30-47 days

Time to steady-state: 14 days

Mean accumulation ratio: N/A

Terminal phase half-life: 75 to 94 hours

Abilify has an oral bioavailability of 87 percent. It is readily absorbed with peak plasma concentrations in three to five hours. The body eliminates this drug via the liver. 


What is the half-life of Abilify?

It is between 75 to 94 hours and for the long acting injection formulation 30-47 days.

How long does Abilify stay in your system?

Abilify is detectable in your system for the following time frames:

Since Abilify is not a drug often abused, it is rarely tested for, so it’s unclear how long it might show up in standard urine, saliva, or hair tests. There have been a few false positives for amphetamine drug screens for people taking Abilify, but incidents appear to be rare. 

Can I stop Abilify suddenly?

Abilify changes the way the brain manages certain chemicals, so people taking it should not stop suddenly. A medical provider can provide a plan to reduce doses over a few weeks to prevent withdrawal. 

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.

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