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Topamax is approved for use in treating seizures and preventing migraines. Topamax for bipolar disorder is considered an off-label use of this medication. Those who plan to take Topamax to manage bipolar disorder should be aware of potential side effects and dosage information and should talk with their doctor.

*If you experience suicidal thoughts, a symptom that may occur with this medication, seek help or call 911 immediately if you are in danger.

Dosage – How much Topamax should I take for bipolar?

The amount of Topamax that should be taken for bipolar disorder may vary from one person to another. Topamax dosages for seizures can be up to 400 mg per day in two doses, while Topamax for migraines can be 100 mg per day in two doses. Individuals taking Topamax for bipolar disorder should follow their doctor’s recommended dosages.

Side Effects

Topamax can cause certain side effects, such as weight loss, tingling or numbness, dizziness, problems with memory, and problems with concentration. Other side effects, such as mood changes or hearing problems, are more rare. Suicidal thoughts and ideation are other possible side effects.


Can Topamax be used as a mood stabilizer?

Topamax may be used as a mood stabilizer for those who have bipolar disorder, although this is considered an off-label use for this medication. A 2000 study showed that Topamax may be effective at stabilizing mood in those with bipolar disorder. However, more research is needed to better understand its effects on this mood disorder.

What is the best mood stabilizer for bipolar?

Several mood stabilizers are available for bipolar disorder, such as lithium, valproic acid, carbamazepine, lamotrigine, and divalproex sodium. The mood stabilizer that works best will vary from person to person depending on certain factors, such as the severity of their condition. Those who need a mood stabilizer for bipolar disorder should discuss options with their doctor.

Can Topamax make you manic?

Topamax may cause mood changes in some individuals. A 2019 case report showed that a patient experienced mania while taking Topamax. This patient has bipolar disorder and a binge-eating disorder. Additional research is needed to better understand the risks of Topamax for those who have bipolar disorder.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.

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