OverviewDosageSide EffectsInteractionsHalf-Life

Just like with any other medication, it is critical to discuss the risks consuming alcohol during your treatment with fluoxetine. Your doctor will be able to assess what is safe for you.

Please note: it is generally not safe or recommended to consume alcohol during treatment with fluoxetine.

Can you drink alcohol on antidepressants?

The FDA states that patients should always inform their doctor if they are taking other medication(s), including prescription and/or over-the-counter medications, herbal supplements, or consuming alcohol. The FDA further states to avoid consuming alcohol while taking fluoxetine. Serious side effects may occur when fluoxetine and alcohol interact.

What happens if you drink alcohol while taking fluoxetine?

As mentioned above, it is not safe or recommended to drink alcohol while taking fluoxetine because severe side effects could occur. Mayo Clinic states such side effects can include:

  • Counteraction or exacerbation of anxiety and/or depression symptoms
  • Interactions-including heightened blood pressure-with any additional medications you take, such as monoamine oxidase inhibitors (MAOIs)
  • Drowsiness
  • Impairment in judgement and thinking
  • An increased risk of alcohol abuse
  • Difficulty sleeping

Mayo Clinic further states the importance of seeking professional help if you believe you have a substance abuse problem. Talk to your doctor about alternative treatments/medications, including lifestyle changes and seeking counseling.

What is the best time of day to take fluoxetine?

For more information on dosing fluoxetine, please visit our dosing page. If you have specific questions about the best time of day to take your medication, consult your prescribing physician or a pharmacist for guidance.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.


More about Fluoxetine

Written by

Medically reviewed by