Below are the general guidelines for dosing Jardiance (empagliflozin). Note that these dosages may be adjusted on a case-by-case basis for individual patients. Always follow your prescribing physician’s instructions for taking Jardiance.
The following information comes from DailyMed, an FDA label information provider.
What if I miss a dose of Jardiance?
According to Mayo Clinic, if you miss a dose of Jardiance take it immediately unless you are closer in time to your next dose. Never double doses.
What if I overdose on Jardiance?
In the event of an overdose with JARDIANCE, contact the Poison Control Center. Employ the usual supportive measures (e.g., remove unabsorbed material from the gastrointestinal tract, employ clinical monitoring, and institute supportive treatment) as dictated by the patient’s clinical status. Removal of empagliflozin by hemodialysis has not been studied.
Dosage and Administration
2.1 Recommended Dosage
The recommended dose of JARDIANCE is 10 mg once daily in the morning, taken with or without food. In patients tolerating JARDIANCE, the dose may be increased to 25 mg after 4 – 12 weeks . [see CLINICAL STUDIES (14)].
In patients with volume depletion, correcting this condition prior to initiation of JARDIANCE is recommended [see WARNINGS AND PRECAUTIONS (5.1), USE IN SPECIFIC POPULATIONS (8.5) and PATIENT COUNSELING INFORMATION (17)].
2.2 Patients with Renal Impairment
Assessment of renal function is recommended prior to initiation of JARDIANCE and periodically thereafter.
JARDIANCE should not be initiated in patients with an eGFR less than 45 mL/min/1.73 m2.
No dose adjustment is needed in patients with an eGFR greater than or equal to 45 mL/min/1.73 m2.
JARDIANCE should be discontinued if eGFR is persistently less than 45 mL/min/1.73 m2[see WARNINGS AND PRECAUTIONS (5.1, 5.3) and USE IN SPECIFIC POPULATIONS (8.6)]. (contraindicated with eGFR < 30 or in hemodialysis)
How is Jardiance supplied?
JARDIANCE tablets are available in 10 mg and 25 mg strengths as follows:
10 mg tablets: pale yellow, round, biconvex and bevel-edged, film-coated tablets debossed with “S 10” on one side and the Boehringer Ingelheim company symbol on the other side.
Bottles of 30 (NDC 0597-0152-30)
Bottles of 90 (NDC 0597-0152-90)
Cartons containing 3 blister cards of 10 tablets each (3 × 10) (NDC 0597-0152-37), institutional pack.
25 mg tablets: pale yellow, oval, biconvex film-coated tablets, debossed with “S 25” on one side and the Boehringer Ingelheim company symbol on the other side.
Bottles of 30 (NDC 0597-0153-30)
Bottles of 90 (NDC 0597-0153-90)
Cartons containing 3 blister cards of 10 tablets each (3 × 10) (NDC 0597-0153-37), institutional pack.
Dispense in a well-closed container as defined in the USP.
Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F) [see USP Controlled Room Temperature].
Generic Name: Empagliflozin
Class: Sodium-glucose cotransporter 2 (SGLT2) inhibitors
Availability: Prescription only (currently in the United States, no generic version is available)
Molecular Formula: C23H27ClO7
Substance UNII: HDC1R2M35U
What is Jardiance?
Jardiance is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It is the brand name of the drug empagliflozin.
What is Jardiance Used For?
Jardiance is used for the treatment of diabetes. It was approved by the U.S. Food and Drug Administration (FDA) in 2014.
According to the U.S. National Library of Medicine, Jardiance can also help lower the risk of heart attack, stroke, and death in people with type 2 diabetes who also have heart and blood vessel diseases.
How Does Jardiance Work?
Jardiance helps lower blood sugar in people with type 2 diabetes. It’s meant to be used along with diet and exercise. It works by helping the kidneys send excess sugar out of the body through the urine.
How Long Does it Take for Jardiance to Work?
Jardiance may start to help lower blood sugar levels within 1 to 2 weeks. But studies suggest it may take up to 24 weeks for a person to get the full benefits of Jardiance.
Do Not Use Jardiance If:
There are several situations where this medication may not be the right choice for you. According to the FDA, the following should not use Jardiance:
- People with type 1 diabetes
- People with allergies or sensitivities to ingredients in Jardiance
- People with severe or end-stage kidney disease, including people who are on dialysis
- People with diabetic ketoacidosis (a serious health condition that can occur if high blood sugar is left untreated)
Please note that this list may not be complete, and there may be other situations where the use of this drug is not advisable.