OverviewDosageSide EffectsInteractionsHalf-Life

Negative effects of Jardiance (empagliflozin) and pregnancy have been observed in animal studies. Due to the potential risks of harm to a developing fetus, the FDA and other organizations including the manufacturer do not advise taking Jardiance (empagliflozin) during second and third triemesters.

Jardiance and Breastfeeding

Nonhuman animal studies show that Jardiance can cross into the breast milk of lactating and nursing mothers. Due to the possible health risks to a nursing infant, it is not recommended to take Jardiance while breastfeeding or lactating.

FAQ

When should you not take Jardiance?

Pregnant patients should not take Jardiance while pregnant during second and third trimesters. If they are taking Jardiance when they become pregnant, they should speak with their medical provider. The medical provider may recommend that the pregnant parent try a different medication to help them manage their type 2 diabetes.

Is Jardiance safe for pregnancy?

There is limited evidence on the safety of Jardiance during pregnancy in humans. Based on nonhuman animal research, however, Jardiance is not considered safe to take in the second and third trimesters. 

Is empagliflozin safe?

Empagliflozin is generally considered safe and, compared to other blood sugar-lowering medications used for type 2 diabetes, empagliflozin may actually be less likely to cause hypoglycemia (low blood sugar). Like any medication, empagliflozin does come with the risk of possible side effects and may not be safe for all people. Patients should discuss their risks of these complications with their prescribing medical provider.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.



OVERVIEW
DOSAGESIDE EFFECTSINTERACTIONSHALF-LIFE

Generic Name: Empagliflozin

Brands: Jardiance

Class: Sodium-glucose cotransporter 2 (SGLT2) inhibitors

Availability: Prescription only (currently in the United States, no generic version is available)

Molecular Formula: C23H27ClO7

Substance UNII: HDC1R2M35U

What is Jardiance?

Jardiance is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It is the brand name of the drug empagliflozin.

What is Jardiance Used For?

Jardiance is used for the treatment of diabetes. It was approved by the U.S. Food and Drug Administration (FDA) in 2014

According to the U.S. National Library of Medicine, Jardiance can also help lower the risk of heart attack, stroke, and death in people with type 2 diabetes who also have heart and blood vessel diseases.

How Does Jardiance Work?

Jardiance helps lower blood sugar in people with type 2 diabetes. It’s meant to be used along with diet and exercise. It works by helping the kidneys send excess sugar out of the body through the urine. 

How Long Does it Take for Jardiance to Work?

Jardiance may start to help lower blood sugar levels within 1 to 2 weeks. But studies suggest it may take up to 24 weeks for a person to get the full benefits of Jardiance.

Do Not Use Jardiance If:

There are several situations where this medication may not be the right choice for you. According to the FDA, the following should not use Jardiance:

  • People with type 1 diabetes
  • People with allergies or sensitivities to ingredients in Jardiance
  • People with severe or end-stage kidney disease, including people who are on dialysis
  • People with diabetic ketoacidosis (a serious health condition that can occur if high blood sugar is left untreated)

Please note that this list may not be complete, and there may be other situations where the use of this drug is not advisable.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.


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