Jardiance (empagliflozin) was the 228th most commonly prescribed drug in the United States in 2017. In that year alone, there were over 2,223,050 prescriptions for this medication issued. Considering how popular this drug is right now, it pays to know a little bit more about this medication, including how long Jardiance stays in your system.
The FDA states the following information regarding Jardiance half-life:
Time to peak plasma concentration: 1.5 hours post-dose
Terminal phase half-life: 12.4 hours
Jardiance has an oral bioavailability of about 78 percent. Most of the drug is eliminated from the body via the feces (about 41.2 percent) or urine (about 54.4 percent).
What is the half-life of Jardiance?
The half-life of Jardiance is 12.4 hours.
How long does Jardiance stay in your system?
Jardiance may stay in your system for about 8 to 10 days after the last dose. Jardiance can take longer to clear out of the body of people with certain health conditions, including impaired kidney function.
How long does it take for Jardiance to lower A1C?
Research suggests it takes about 24 weeks for the drug Jardiance to lower a person’s A1C by about 0.7 percent to 0.8 percent. Bodyweight and fasting blood sugar levels have also been shown to decrease in this amount of time. A1C is a way to measure how well a person’s blood sugar levels are controlled over time.
Is Jardiance long-acting?
Jardiance has a more long-acting effect on blood sugar compared to other diabetes medications and is intended to be used over the long term.
Generic Name: Empagliflozin
Class: Sodium-glucose cotransporter 2 (SGLT2) inhibitors
Availability: Prescription only (currently in the United States, no generic version is available)
Molecular Formula: C23H27ClO7
Substance UNII: HDC1R2M35U
What is Jardiance?
Jardiance is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It is the brand name of the drug empagliflozin.
What is Jardiance Used For?
Jardiance is used for the treatment of diabetes. It was approved by the U.S. Food and Drug Administration (FDA) in 2014.
According to the U.S. National Library of Medicine, Jardiance can also help lower the risk of heart attack, stroke, and death in people with type 2 diabetes who also have heart and blood vessel diseases.
How Does Jardiance Work?
Jardiance helps lower blood sugar in people with type 2 diabetes. It’s meant to be used along with diet and exercise. It works by helping the kidneys send excess sugar out of the body through the urine.
How Long Does it Take for Jardiance to Work?
Jardiance may start to help lower blood sugar levels within 1 to 2 weeks. But studies suggest it may take up to 24 weeks for a person to get the full benefits of Jardiance.
Do Not Use Jardiance If:
There are several situations where this medication may not be the right choice for you. According to the FDA, the following should not use Jardiance:
- People with type 1 diabetes
- People with allergies or sensitivities to ingredients in Jardiance
- People with severe or end-stage kidney disease, including people who are on dialysis
- People with diabetic ketoacidosis (a serious health condition that can occur if high blood sugar is left untreated)
Please note that this list may not be complete, and there may be other situations where the use of this drug is not advisable.