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If you’ve had vaginal atrophy (aka vaginal dryness), you’re familiar with how it can make you uncomfortable and disrupt your sex life, but products like Revaree and Replens can help bring back moisture and protect delicate skin.

This article will discuss the differences between Revaree vs. Replens and see which works better for vaginal dryness.

Revaree Vs Replens

After comparing Revaree and Replens we have determined that Revaree offers a longer lasting solution to vaginal dryness.

While Replens is more of a temporary solution that last up to 3 days, Revaree is attempts to tackle the causes of dryness over time. Studies found that within 9 days Revaree had relieved vaginal dryness and painful sex.

Quick Look – The Differences Between Revaree & Replens

Revaree and Replens are both designed to address vaginal dryness, but they differ in their formulation, application, and specific use cases:

  1. Formulation: Revaree is a vaginal suppository that uses hyaluronic acid as its active ingredient, a compound that research supports for relieving vaginal dryness​​. It is hormone-free, which makes it an attractive option for women who prefer to avoid hormonal therapies. On the other hand, Replens is a cream-type vaginal moisturizer that attaches to dry vaginal cells to deliver long-lasting moisturizing effects. It also offers other products for external use and sexual lubrication​.
  2. Application: Revaree is inserted into the vagina every 2-3 days before bedtime​​, while Replens Long-Lasting Vaginal Moisturizer is applied inside the vagina with a reusable applicator once every 2-3 days​.
  3. Use cases:
    • Revaree is often recommended for women experiencing menopause or other factors that can affect estrogen levels, such as postpartum and breastfeeding, certain medications, cancer treatments, and psychological stress. It’s an excellent choice for those who wish to support their vaginal health but are uncomfortable with hormonal therapies​​.
    • Replens Long-Lasting Vaginal Moisturizer is a good option for those seeking sustained relief from vaginal dryness. It’s also suitable for individuals who prefer a cream-type product and may appreciate the extended duration of effect. Replens also offers external comfort gel for external vaginal skin irritation and a lubricant for use before or during sex​​.
  4. Side Effects: While both products are generally well-tolerated, some users of Replens have reported side effects like vaginal infections, painful urination, burning, unusual vaginal discharge, and muscle spasms​. It’s important to note that individual experiences may vary, and anyone considering these products should consult with a healthcare provider.
  5. Cost: Revaree is a higher-end product, costing around $60 per box​​, while Replens is more affordable, with a price of around $15​​. The choice between the two may also depend on individual budget considerations.
  6. Customer Feedback: Revaree has received positive reviews for its life-changing effects and improvement in sexual function​​, while reviews for Replens are mixed, with some users finding success and others finding the product ineffective or having side effects​​.

Vaginal Dryness – Causes & Symptoms

Vaginal dryness is a painful symptom that affects a person’s quality of life. It occurs when the tissues in the vagina are dry, thin, and not well-moisturized, leading to discomfort and irritation, especially during sex.

A dry vagina may also cause:

  • Burning and itching.
  • Bleeding after sex
  • Decreased libido
  • Soreness in the vulva
  • Frequent urination
  • Recurrent urinary tract infections (UTIs) or yeast infections.

Vaginal dryness can occur at any age, but it’s most common in women during or after menopause when estrogen levels normally start to decline. The hormone estrogen helps keep your vaginal lining moisturized and healthy; low levels of this hormone can cause the lining to become thin and dry. 

What is Revaree

Revaree Hyaluronic Acid Vaginal Dryness Suppository is a product manufactured by Bonafide, a pharmaceutical company specializing in creating products that help treat women’s health problems like menopause, PMS & intimacy issues, using all-natural ingredients to maximize efficiency and relief.

Revaree provides effective, hormone-free relief from vaginal atrophy with an easy-to-use, applicator-free vaginal suppository that renews your body’s moisture for everyday comfort and intimacy. 

Revaree uses hyaluronic acid (HA), a powerful, scientifically-validated molecule naturally produced throughout the body and promotes cell hydration and healing. Here, the product attracts and retains moisture in the vaginal lining, creating a healing environment that repairs and restores thinning and damaged tissue for lasting moisture and relief.

What is Replens 

Replens is a company that manufactures vaginal moisturizers and lubricants to help reduce the symptoms of vaginal dryness. Its parent company is Church & Dwight Co., Inc., which owns other popular personal care brands such as First Response, Nair, RepHresh, and Trojan.

Replens’ Long-Lasting Vaginal Moisturizer is an over-the-counter (OTC) vaginal moisturizer designed to replenish internal vaginal moisture and provides long-lasting results that last up to three days — all without estrogen, supplementing the body’s natural lubrication so that you can regain comfort and confidence. 

This moisturizer has a bioadhesive that helps the product attach to dry vaginal cells

to deliver continuous moisture, which the cells absorb to regain their natural integrity and elasticity. It coats to provide immediate relief to dry vaginal lining cells while the dead vaginal lining cells are eliminated, and tissue is left to moisturize and rejuvenate itself. 

Benefits of Revaree 

Revaree provides effective, hormone-free relief from vaginal atrophy with hyaluronic acid (HA), a powerful molecule that promotes cell hydration and healing and renews your body’s moisture for everyday comfort and intimacy by attracting and retaining moisture in the vaginal lining. This environment allows for the repair and restoration of thinned and damaged tissue to ensure lasting moisture. 

The product exclusively contains all-natural ingredients and undergoes meticulous testing to ensure maximum efficiency and safety. Compared to most vaginal suppositories, Revaree is easy to use and doesn’t require an applicator for vaginal insertion. 

Benefits of Replens 

Replens’ Long-Lasting Vaginal Moisturizer replenishes internal vaginal moisture and provides long-lasting results that last up to three days — all without estrogen. It contains polycarbophil and glycerin as its main ingredients, which both effectively restore and maintain lubrication in the vagina for long periods of time. 

Replens stands apart from other creams or lubricants because it contains a patented bio-adhesive ingredient that allows it to attach to dry cells and coats to provide immediate relief and deliver continuous moisture to dry vaginal lining cells while the dead vaginal lining cells are eliminated, while the tissues become moisturized and rejuvenated. 

Unlike most products, Replens works well with condoms like natural rubber latex, polyisoprene, and polyurethane.

Side Effects

Revaree Side Effects

As of date, clinical studies have reported that no serious adverse effects have occurred so far. The FDA also classifies Revaree as a Class II Medical Device, with over a million women across the globe having safely used this formulation. 

However, each woman has a different response to the product, and using vaginal suppositories, in general, has its cons, such as:

  • Pain in the anal area
  • Leaking
  • Allergic reactions (e.g., skin rash, itching, hives, swelling)
  • Unusual vaginal discharge, itching, or odor.

Women who are not used to vaginal suppositories may find them uncomfortable, as they should be inserted as far into the vagina as possible.

Replens Side Effects

While side effects are rare, some users have reported experiencing the following side effects.

  • Pain at the application site
  • Redness
  • Itching
  • Painful urination
  • Bleeding

Replens also contains other ingredients like sodium hydroxide and methylparaben, which are generally safe under low dosages (as per FDA), but may exacerbate (possible) allergic reactions.

These side effects may occur among those with more sensitive skin. Before trying out the product, it’s always best to test it on a small patch of skin; should adverse effects occur, consult your healthcare provider as soon as possible.  

Revaree and Replens Product Comparison 

Here, let’s check how one product fares against the other:

Ingredient Quality 

Revaree contains hyaluronic acid, which studies prove reduces vaginal dryness while keeping the microbiome and pH levels normal, and is often used as a treatment option for menopausal women and those who experience vaginal dryness from contraceptives or birth control. Among other things, Revaree uses exclusively all-natural ingredients for maximum efficiency.

The active ingredient in the Replens is polycarbophil, which moisturizes vaginal tissue and relieves discomfort. Another ingredient, glycerin, assists in maintaining moisture for long periods of time. 

✅ Winner: Revaree

Product Safety

Revaree has been thoroughly tested for safety, efficacy, and potency. Bonafide manufactures its products in a GMP-certified manufacturing facility and stringently tests them for microbiological contaminants and allergens to ensure product safety and quality.

Replens is also tested for and made free from estrogen, preservatives, propylene glycol, or other potentially dangerous chemicals. Results of clinical tests suggest that Replens products are effective. 

Both products are FDA-cleared. 

✅ Winner: Tie


Replens’ have been noted to work almost instantly – retaining moisture for up to 3 days, as proven by clinical studies. A person will only have to top up the Replens moisturizer every 3 days and the external gel once per day.

On the other hand, clinical trials showed that Revaree relieved vaginal dryness and painful sex as early as 9 days. Continued use showed an increase in vaginal moisture and a decrease in painful sex, itching, and burning. Results continue to improve with consistent use.

✅ Winner: Short-term = Replens, Long-term = Revaree

Application Method

Revaree Vaginal Insert Size
Revaree Vaginal Insert Size

Revaree is an applicator-free vaginal insert. Bonafide recommend inserting a single unit using your finger, ideally just before going to bed.

Revaree insertion
Replens Reusable applicator
Replens Reusable applicator

Replens is not an insert that dissolves, it uses an applicator that is inserted into the vagina that delivers the dosage. It is available in a resuable form factor (as shown above) or disposable tubes.

Replens Insertion


As the name implies, Revaree is an easy-to-insert vaginal suppository without needing an applicator to avoid fuss and mess.

While Replens Long-Lasting Vaginal Moisturizer comes in the form of a cream, an applicator is needed to apply the product directly into the vagina to ensure a person is using the right amount.

✅ Winner: Revaree

Brand Reputation 

Bonafide has had 50 years of experience in medical drug discovery, clinical research, and patient advocacy, taking pride in its scientifically-validated, non-prescription, hormone-free products, which are currently recommended by over 7,000 healthcare providers across the country based on its strong data and safety.

Church and Dwight Co., Replens’ parent company, was founded in 1846, has global operations, is listed in the S&P 500, and has manufactured other household-famous products like Arm & Hammer, Batiste, Nair, OxiClean, Trojan, and XTRA, among others. 

✅ Winner: Tie

Compatibility With Contraceptives

Revaree is not compatible with natural rubber latex, polyurethane, or polyisoprene condoms since it may weaken the integrity of the condom.

Replens, on the other hand, is compatible with the above-mentioned condom types.

✅ Winner: Replens

Price Comparison

Revaree can be availed through a 3-month subscription program in which a pack of 10 suppositories is delivered to your door for $42 monthly, while a single purchase costs $62.

The price of a pack of Replens ranges from $15 – $45, depending on its content (8-pack and 14-packs are available). The product is also widely available as an OTC medication in many stores. 

Revaree vs. Replens – What Do The Reviews Say?

Here’s what customers have to say about their experiences after trying Revaree or Replens.

A verified review from an alleged Mindy A. tells her experience with Revaree:

“I’ve been avoiding sex for over a year because it was so painful. I was skeptical at first, but was willing to try anything. After 2 weeks, it was still a little painful, but definitely bearable. Now after a month, sex is once again enjoyable and my husband is pleasantly surprised when I instigate it! Thank you for bringing me and my husband closer than ever!…”

An anonymous customer from Amazon left this review about Replens:

“I like the prolonged moisture. The night after application is the best for comfortable sex. Lasts maybe 3 days. It feels very goopy the night it’s applied and the next morning. It really helps vaginal dryness, but the moisturizer from this company intended for use immediately before sex is amazing- the best I’ve ever used. This one you can’t use immediately before intercourse, so it does hinder spontaneity….”

Frequently Asked Questions

What causes vaginal atrophy?

When the body produces less estrogen, the hormone helps maintain the vagina’s lubrication, elasticity, and thickness. It results in the thinning, drying, and inflammation of the vaginal walls. 

Low estrogen and vaginal dryness often occur during menopause, though estrogen levels can fall after childbirth, with breastfeeding, during cancer treatment, or with anti-estrogen drugs.

Other non-hormonal factors like frequent dosages of cold and allergy medications and some antidepressants can dry out vaginal tissue. 

Can I use vaginal moisturizers with condoms?

Certain vaginal moisturizers may weaken the integrity of certain condom types, like rubber latex or polyurethane. Water- and silicone-based lubricants are best for people who use latex condoms, while petroleum-based products, such as Vaseline, may irritate the tissues in the vulva and vagina. 

Can these vaginal lubricants be used as contraceptives?

As these products don’t contain spermicide, they are not contraceptives. 

Can I use vaginal moisturizers during my period?

Contrary to popular thought, taking vaginal moisturizers/lubricants during a menstrual cycle is safe anytime (the same goes for vaginal suppositories)

Can you use these products before getting a pap smear?

When a product is used sparingly and appropriately, it doesn’t pose much risk to the quality of the pap sample. Excessive amounts, however, can adversely affect it. Some products recommend stopping the usage days before one’s appointment.

Key Takeaways & Recommendations

As a person who’s done extensive research on Revaree and Replens, I can say that both of these products have their unique strengths when it comes to addressing vaginal dryness.

Revaree, a hormone-free vaginal suppository from Bonafide Health, is ideal for those dealing with factors that may change estrogen levels, such as menopause, postpartum and breastfeeding, certain medications, cancer treatments, and psychological stress.

Made with hyaluronic acid, it’s a natural and hormone-free solution. It’s easy to use and has received positive reviews. The product is a bit on the pricier side, with one box of 10 suppositories costing $62, but discounts are available for subscriptions. One thing that’s reassuring is that it’s recommended by over 5,600 doctors​.

On the other hand, Replens offers a range of products including a long-lasting vaginal moisturizer, an external comfort gel, and a silky smooth lubricant. The moisturizer contains a bioadhesive that helps it attach to dry vaginal cells for extended moisture, which can last up to three days. The external comfort gel is designed to reduce irritation around the vagina, and the lubricant is designed to make sex more comfortable. Replens products are more affordable, with the long-lasting vaginal moisturizer priced around $15. However, there have been mixed reviews, with some users reporting issues like unpleasant residue and infections​.

In terms of choosing between the two, it really depends on your individual needs and circumstances. If you’re dealing with conditions that affect estrogen levels and prefer a hormone-free solution, you might lean towards Revaree. It’s been effective for many users, though the cost is higher. If you’re looking for a more affordable range of products, or if you’re specifically interested in an external comfort gel or a personal lubricant, Replens might be a good fit despite some mixed reviews.

As always, consult with your healthcare provider before starting any new health product. They can provide advice based on your specific health history and needs.


Vaginal atrophy/dryness results from a hormone decline, specifically estrogen, which is responsible for keeping the vaginal lining moisturized and healthy. Vaginal moisturizers and lubricants are great options to relieve uncomfortable dryness and itching.

Replens, in particular, has been a proven-and-test popular personal care brand that relieves vaginal dryness. The FDA has cleared Replens, and with clinical studies backing its efficiency. 

Since it’s free from hormones and other harmful chemicals, it’s generally safe for use.

However, if symptoms do not improve after using these products, consult a healthcare provider immediately.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.

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