A veterinarian wrapping a brown and white dog's wound on his paw.

If your dog spends ample time outside, chances are he’s suffered a cut or deep wound. In severe cases, such injuries should be taken up with a veterinarian, who might prescribe medication as part of the healing process. Cefpodoxime is a common antibiotic prescribed to treat skin infections in dogs, including infections that form from unhealed wounds. If you believe your dog has been injured, take them to a veterinarian for care.

What is cefpodoxime?

Cefpodoxime is an antibiotic used to treat various skin infections in dogs.

Is cefpodoxime safe for dogs?

Cefpodoxime is FDA-approved for veterinary medicine, but it might not be right for every dog.


While dosage will differ for every dog, there is a general dosing guideline the FDA outlines:

  • Cefpodoxime proxetil tablets: 2.3-4.5mg per pound of body weight once per day for five to seven days or three to four days beyond the stopping of “clinical signs” for a maximum of 28 days

For more information on dosing, consult your pet’s veterinarian, who will be able to outline the best time and amount to give your dog.

Side Effects

You should be aware that side effects might occur during treatment with cefpodoxime, including but not limited to:

  • Breathing difficulties
  • Vomiting
  • Diarrhea
  • Yeast infection
  • Hives
  • Rash

Please note: this list is not exhaustive. If your dog experiences any side effects with cefpodoxime, call their veterinarian immediately.

Final Thoughts

There are multiple different brands of cefpodoxime, so it’s critical to talk to your pet’s veterinarian about the options. Furthermore, to keep your dog’s safety and health a priority, follow up with their veterinarian both during and after treatment with cefpodoxime. That way, your dog’s veterinarian can monitor your dog’s health and change the treatment if necessary.

Disclaimer: This article does not constitute professional medical advice, nor can it replace the advice of a licensed professional.

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