A dog waiting in the kitchen while staring at pill bottles on the table.

Apoquel for dogs can help reduce itching, particularly scratches related to fleas and allergies. If you do not yet have flea treatment set up for your dog, talk to their veterinarian about available options.

What is Apoquel?

Apoquel is an anti-itch medication for dogs. It can treat:

  • Itching related to fleas
  • Inflammation
  • Allergies
  • Atopic dermatitis

Is Apoquel safe for dogs?

Even though Apoquel is FDA-approved for veterinary use, you should still ask your dog’s veterinarian if it is safe to administer to them. In most cases, this medication is safe for dogs, but safety will also depend on any present health conditions the dog has, as well as any medication(s) they take.

1-800-PetMeds states Apoquell is for use in dogs at least one year old and who weigh at least 6.6 pounds.


Dosage will differ for every dog, and you should ask your veterinarian for personalized dosing instructions. That said, 1-800-PetMeds states the following as a general dosing guideline:

  • ½ of a 3.6mg tablet for dogs 6-6.9 pounds 2x/day
  • ½ of a 5.4mg tablet for dogs 10-14.9 pounds 2x/day
  • 3.6mg tablet for dogs 15-19.9 pounds 2x/day
  • 5.4mg tablet for dogs 20-29.9 pounds 2x/day
  • ½ of a 16 mg tablet for dogs 30-44.9 pounds 2x/day
  • Two 5.4mg tablets for dogs 45-59.9 pounds 2x/day
  • One 16mg tablet for dogs 60-89.9 pounds per day
  • 1.5 16mg tablets for dogs 90-129.9 pounds 2x/day
  • Two 16mg tablets for dogs 130-175.9 pounds per day

Again, please note this list may not be accurate for every dog, and you should always consult a veterinarian for specific dosing instructions.

Side Effects

Your dog may experience certain side effects during treatment with Apoquel, including but not limited to:

  • Infection
  • Digestive problems, including vomiting and/or diarrhea
  • Allergic reactions

If you notice your dog experiencing any side effects, call their vet immediately.

Final Thoughts

As with any other medication, you should proceed with caution and safety in mind when thinking about administering Apoquel to your dog. Talk to your veterinarian about alternative treatments and medications, as well as potential risks and benefits of administering the drug to your dog. And as always, call your veterinarian if your dog experiences any problems with the medication.

Disclaimer: This article does not constitute professional medical advice, nor can it replace the advice of a licensed professional.

Written by