If you are pregnant, think you are pregnant, or plan to become pregnant, talk with your doctor before starting treatment with Trulicity (dulaglutide). The FDA states Trulicity should only be prescribed to pregnant women if the potential benefit outweighs the potential risk to the developing baby. As of now other medications other than dulaglutide are recommended to treat type 2 diabetes mellitus during pregnancy.
Trulicity, Labor and Delivery
The FDA states that pre-gestational diabetic women with an HbA1c>7 face a 6-10% risk of major birth defects. Pre-gestational diabetic women with an HbA1c>10 face a 20-25% risk of major birth defects. Always consult with your physician before taking Trulicity if you are pregnant, as both diabetes and various medications have the potential to have adverse effects on the developing baby.
Can Trulicity cause birth defects?
The FDA states that due to limited data, the effect of Trulicity on a miscarriage or birth defects in human fetuses is hard to determine. Based on animal reproduction studies, however, it is possible there may be risks to the developing fetus from exposure to Trulicity during pregnancy.
Can Trulicity cause a miscarriage?
Again, the FDA states that due to limited data, the effect of Trulicity on a miscarriage or birth defects in human fetuses is hard to determine. Therefore, it is best to proceed with caution when thinking about taking Trulicity during pregnancy.
Trulicity and Lactation
Not enough data exists to determine if Trulicity can be present in human breast milk, nor is there enough data to determine the effects of Trulicity on a breastfeeding infant.
When deciding whether or not to take Trulicity during breastfeeding, the prescribing physician should determine if the risks of taking Trulicity outweigh the benefits of breastfeeding for the infant.
Trulicity and Fertility
In rat studies, when Trulicity was administered at 16.3 mg/kg, no adverse effects were observed on sperm, mating, fertility, conception, or embryonic survival, according to the FDA.
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