Hydrochlorothiazide and alcohol interactions can occur. Specifically, consuming alcohol while taking hydrochlorothiazide can cause orthostatic hypotension, a serious condition that causes a person’s blood pressure to drop when they sit up or stand up quickly.
Taking hydrochlorothiazide and alcohol can cause the following side effects:
- Orthostatic hypotension (postural low blood pressure)
Hydrochlorothiazide and alcohol can interact in ways that enhance the antihypertensive, or blood pressure-lowering, effect of hydrochlorothiazide. Namely, this interaction can cause headache, dizziness, lightheadedness, fainting, and changes in a person’s heart rate and blood pressure.