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While experts have not found extensive evidence that levothyroxine and alcohol interact negatively with each other, most medical providers advise against drinking too much alcohol when consuming this or any drug. Plus, certain side effects of levothyroxine (including flushed skin, headaches, or sweating) may be exacerbated by drinking too much alcohol. 

Side Effects

A person drinking too much alcohol while taking levothyroxine may experience worsening levothyroxine side effects, such as headaches or flushed skin. In some people, levothyroxine can also cause vomiting and diarrhea, which may lead to dehydration. Drinking alcohol may worsen dehydration.


There are no documented interactions between levothyroxine and alcohol. But, this fact doesn’t mean no interactions are possible. Plus, drinking too much alcohol may lead to damaging effects that can further impair your quality of life and overall health.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.

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