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There are currently no reported interactions between Xeljanz (tofacitinib) and alcohol. However, serious interactions can occur for those simultaneously taking methotrexate [Otrexup (PF), Xatmep, Trexall] with Xeljanz.


Since every patient is different, there is no set amount regarding how much alcohol a person can consume while taking methotrexate. Experts advise avoiding alcohol while taking this drug, though.

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