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While Entyvio (vedolizumab) is not known to have any addictive effects, abruptly stopping its use may lead to withdrawal symptoms. Those who receive these injections for Crohn’s disease or ulcerative colitis should be aware of Entyvio withdrawal effects that could occur.

How Long Do Entyvio Withdrawal Symptoms Last?

The symptoms that individuals might experience and how long these occur after stopping the use of Entyvio may vary. Keep in mind that Entyvio is sometimes used along with other medications to manage Crohn’s disease or ulcerative colitis. If Entyvio use is stopped, symptoms of these conditions might return.

Withdrawal Symptoms

No specific symptoms of withdrawal have been associated with Entyvio. However, stopping the use of this medication could cause symptoms of Crohn’s disease or ulcerative colitis to return or worsen.


Some individuals might begin to experience symptoms of ulcerative colitis or Crohn’s disease after stopping the use of Entyvio. Those who take Entyvio should discuss the risks of stopping its use with a healthcare provider.  This is particularly important for women who are pregnant, since clinical studies show that uncontrolled active Crohn’s disease may raise the risk of pregnancy complications or birth defects.

Treatment Options

Individuals who plan on stopping the use of Entyvio should first go over other treatment options for Crohn’s disease or ulcerative colitis with a healthcare provider. It’s important to continue managing the symptoms of these conditions.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.

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