Amoxicillin is currently the 18th most commonly prescribed drug in the United States. In 2017 alone, there were almost 28 million prescriptions. Considering how popular this drug is right now, it pays to know a little bit more about this medication, including how long Amoxicillin stays in your system.
The FDA states the following information regarding amoxicillin’s half-life:
Mean effective half-life: 61.3 minutes
Time to steady-state: Three days
Terminal phase half-life: 1.27 hours
Amoxicillin has an oral bioavailability of 77.4%. The drug readily diffuses into most body tissues and fluids, but not brain and spinal fluid.
What is the half-life of amoxicillin?
The half-life of amoxicillin is 61.3 minutes.
How long does amoxicillin stay in your system?
Amoxicillin is likely detectable in your system for the following time frames:
- Urine: Roughly 6 to 8 hours after last use, since 60% of the drug is excreted via urine during this time
- Plasma: According to the FDA, up to 8 hours after last use
(Numbers above are merely estimates, and may vary based on several factors, such as age and other medical conditions.)
How long does it take for antibiotics to get out of your system?
Within six to eight hours, 60% of an orally administered dose of amoxicillin is excreted through the urine.
How is amoxicillin metabolized?
Amoxicillin is metabolized by the liver.