Metoprolol was the sixth most commonly prescribed drug in the United States in 2017. In that year alone, there were more than 68,076,157 prescriptions for this medication. Considering the widespread use of metoprolol, it is important to understand how long metoprolol stays in the body.
DurgBank states the following information regarding metoprolol half-life:
Mean effective half-life: 3 to 7 hours
Administered orally, metoprolol has a bioavailability of about 50 percent; intravenous (IV) administration of metoprolol has a bioavailability of 100 percent. This means the body can absorb about half of the metoprolol available in a pill and all of the medication from an IV. The liver breaks down metoprolol, and the body eliminates the drug through urine. The drug does not accumulate in the body.
What is the half-life of metoprolol?
The half-life of metoprolol is 3 to 7 hours, according to DrugBank.
How long does metoprolol stay in your system?
Lab tests can detect metoprolol in the blood. The normal range for LabCorp metoprolol blood tests is 30−280 ng/mL; reference ranges for other testing laboratories may differ. At a half-life of 3 to 7 hours, metoprolol is out of the system in about one day.
What is the peak time for metoprolol?
Metoprolol reaches its peak effect one to two hours after oral administration, and 20 minutes after intravenous (IV) administration when infused over 10 minutes.
How long does it take to get beta-blockers out of your system?
The body eliminates most beta-blockers quickly, usually within a day.