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Oxycodone and acetaminophen are both medications for pain management. They are sometimes paired to improve the effect of pain. The brand name for oxycodone and acetaminophen is Percocet. 

Oxycodone and Acetaminophen – Potential Interactions

There is some indication that the combination of oxycodone and acetaminophen might be related to acetaminophen overdoses and liver damage. People taking combination drugs like Percocet may not realize it contains acetaminophen. They may unintentionally take over-the-counter products like Tylenol and overdose.

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