OverviewDosageSide EffectsInteractionsHalf-Life

Generic Name: Pregabalin

Brands: Lyrica

Class: Anticonvulsant

Availability: Prescription only

Molecular Formula: C8H17NO2

Substance UNII: 55JG375S6M

What is Pregabalin?

Pregabalin (Lyrica) is an anticonvulsant. It is often sold under the trade name Lyrica, and is a controlled substance (schedule V).

What is Pregabalin Used For?

Pregabalin is approved for use in managing neuropathic pain caused by diabetic peripheral neuropathy or spinal cord injuries. This medication is also used to manage postherpetic neuralgia and fibromyalgia. Pregabalin is also used as adjunctive therapy for treating partial onset seizures in individuals who are at least 1 month old. Pregabalin also has many off label uses.

How Does Pregabalin Work?

The exact mechanism of action for pregabalin is unknown. However, it might help relieve pain by decreasing nerve signals, which helps reduce pain sensation in cells that have a higher sensitivity. Studies done on mice showed that pregabalin binds to the alpha2-delta site in tissues in the central nervous system, which might contribute to its anticonvulsant effects.

How Long Does It Take for Pregabalin to Work?

The time it takes for pregabalin to work may vary depending on certain factors, such as the severity of pain or the dosage taken. Some individuals might begin to experience pain relief after taking this medication for 1 or 2 weeks.

Do Not Use Pregabalin If:

There are several situations where this medication might not be the right choice for you. According to the FDA, the following should not use pregabalin:

  • Those who have a hypersensitivity to pregabalin or one or more of its components

Please note that this list may not be complete, and there may be other situations where use of this drug is not advisable.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.


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