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The use of pregabalin during pregnancy has not been adequately studied in humans. Pregabalin and pregnancy risks should be taken into consideration before this medication is used in pregnant women. Pregabalin does cross the placenta.

Studies on animals showed problems with fetal development, such as skeletal malformations and decreased body weight. The dosages used in these studies were 16 times higher than the maximum recommended dosage of 600 mg per day for humans. Dosages that produced no effects in fetuses in animal studies were around twice the maximum recommended dosages for humans. Women who are pregnant or who plan on getting pregnant should discuss potential risks to fetuses with their doctor before taking this medication.

Pregabalin and Breastfeeding

The use of pregabalin in women who are nursing is not recommended due to potential risks, such as an increased risk of tumor development that was observed in studies done on lactating animals. Small amounts of this medication have been found in human breast milk with average steady-state concentrations of around 76 percent. More research is needed on the potential risks of pregabalin on breastfed human infants and on milk production in humans.


What is the best painkiller to take during pregnancy?

Some over-the-counter and prescription pain medications are considered unsafe to take during pregnancy, such as ibuprofen and aspirin. Women who are pregnant should ask their doctor for recommendations on the safest pain medications to take during pregnancy. For example, acetaminophen is generally considered safe to take during pregnancy.

Is pregabalin safe while breastfeeding?

Pregabalin is not recommended for women who are breastfeeding due to potential risks to breastfed infants. Women who are planning to nurse should discuss these risks with their doctor.

Is pregabalin safe during pregnancy?

Pregabalin should only be taken during pregnancy after discussing the potential risks with a doctor. There is not enough research on the use of this medication in pregnant women.

What medications affect breastfeeding?

Many medications can pass to breast milk at least in small amounts, although this may not raise the risk of harmful effects in infants. Women who are nursing or planning to nurse should ask their doctor for medications that are safe to take while breastfeeding. Examples of medications that are considered safe for nursing women include acetaminophen and ibuprofen.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.

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