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Patients should not stop taking amlodipine without checking with their doctor first. Suddenly stopping this medication may lead to a variety of withdrawal symptoms. 

How Long Do Amlodipine Withdrawal Symptoms Last?

Because amlodipine can take up to 11.5 days to fully leave the body, patients may experience side effects and withdrawal symptoms for about this long after their last dose.

Withdrawal Symptoms

Possible withdrawal symptoms of amlodipine include increasing blood pressure or increased chest pain (angina).


Certain people may be at greater risk of experiencing amlodipine withdrawal symptoms, including people with congestive heart failure, impaired liver function, and eldery people. 

Treatment Options

The best way to reduce the risk of amlodipine withdrawal symptoms is to wean off the medication slowly under the direct supervision of a medical professional. If patients experience issues like high blood pressure or chest pain while coming off amlodipine, a doctor may prescribe other blood pressure medications or lifestyle changes to better manage patient symptoms. For example, people with angina may be instructed to take nitroglycerin (Rectiv, Nitro-Time, Nitrolingual) to relieve their chest pain symptoms.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.

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