Doxepin and alcohol interactions can occur.
Drinking alcohol while taking doxepin will likely enhance the sedative side effects of both. Since they both impair motor function and coordination, people taking both simultaneously can experience intense impairment and incoordination. It would be unwise to drive a car or perform any activity that requires focus, balance, and coordination during combined use.
Both alcohol and doxepin depress the central nervous system. So, taking them both together doubles side effects like drowsiness and poor motor function.