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Baclofen may not be the right choice for every patient. In such cases, it is important to discuss with a medical provider potential baclofen alternatives.

Baclofen Alternatives

For Anxiety

Baclofen calms people with anxiety by making them sleepy. Other drugs that can have this same effect include medications more commonly used for anxiety, such as lorazepam (Ativan), or medications like zoloft.

For Alcohol Withdrawal

Benzodiazepines are more common these days for alcohol withdrawal than baclofen. Some examples of benzos used for alcohol withdrawal include diazepam (Valium) and chlordiazepoxide (Librium). 

For Hiccups

The only FDA approved medication for hiccups is chlorpromazine (Thorazine). The typical dose of Thorazine for hiccups starts at 25 mg four times a day. 

For Muscle Spasms

The standard treatment for muscle spasms is tizanidine (Zanaflex). Another possibility is cyclobenzaprine (Flexeril). Both medications will provide the same relief as baclofen, although they have different mechanisms of action. For example, Flexeril works to relieve spasms at the brain stem, as opposed to the spine like baclofen. 

For Neck Pain

Cyclobenzaprine (Flexeril) is a muscle relaxant often prescribed for this kind of muscle pain. It works by blocking certain nerves messages at the brain stem. 

For Dogs

Baclofen should not be given to dogs. It is toxic to both canines and felines. Instead, a vet might prescribe methocarbamol (Robaxin) for dogs, which works in a similar fashion but is safer. 

Never give any medications to pets without authorization from a veterinarian.

For Sleep & Insomnia

Sleepiness is a side effect of baclofen, but that is true for many drugs. Lorazepam (Ativan), given for anxiety, will have the same effect.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.

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