OverviewDosageSide EffectsInteractionsHalf-Life

Metformin may not be the right choice for every patient. In such cases, it is important to discuss with a doctor potential metformin alternatives.

Metformin Alternatives

What are your options when it comes to alternatives for metformin?

For PCOS

Clinical studies show that thiazolidinedione (TZD), also know as glitazones, can have an impact on diabetes and help restore women’s menstrual periods. The drug works by activating key receptors that make cells more dependent on glucose.  

For Diabetes

There are multiple metformin alternatives available such as Prandin (repaglinide), which is a meglitinide used to control blood sugar. Invokana (canagliflozin) is a drug that lowers blood sugar and reduces the risk of cardiovascular disease, as does Farxiga (dapagliflozin). 

Natural Alternatives

Some natural alternatives for metformin include bitter gourd, which has been used as part of traditional Indian medicine for centuries. Gymnema Sylvestre (cowplant) is a staple in Ayurvedic medicine used for both type 1 and type 2 diabetes management. 

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.


More about Metformin

Written by

Medically reviewed by