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There is some indication that metformin and weight loss might go together, although it is not a quick fix for obesity. One study found it may take one to two years to see much change. The higher the BMI, the more effective the drug is for weight loss, though. 

Metformin and Weight Loss – Does it Work?

It’s not clear why taking metformin might promote weight loss. One theory is it acts as an appetite suppressant. Another suggests that it changes the way the body stores fat. 


The dose will vary based on specific factors such as BMI and body weight. Generally, it is between 500 to 1,000 mg per day and does not exceed 2,500 mg per day. The dose may start small and increase over time, as well. 

Side Effects

  • Nausea
  • Abdominal bloating
  • Gas
  • Vomiting
  • Diarrhea
  • Headache
  • Dizziness

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