OverviewDosageSide EffectsInteractionsHalf-Life

Mirtazapine and pregnancy are a potentially problematic combination. People who suspect they are pregnant should tell their medical providers if taking this medication, as there is some indication that it may cause issues with the fetus. Mirtazapine does cross the placenta, but the data available is inconclusive. A medical provider will decide if taking mirtazapine is necessary to ensure the health of the parent despite the risk to the fetus. 

Mirtazapine and Breastfeeding

Mirtazapine passes through breast milk in small amounts and may lead to some side effects like sleepiness. It is generally considered safe for nursing mothers, though, when recommended by a healthcare professional.


What antidepressants can you take while pregnant?

It is up to a physician to decide what medications are right for a pregnant patient. Some common choices to treat depression during pregnancy include selective serotonin reuptake inhibitors (SSRIs) such as Zoloft (sertraline), serotonin and norepinephrine reuptake inhibitors (SNRIs) like Cymbalta (duloxetine). Always follow your physicians instructions when it comes to any medications during pregnancy.

What medications are not safe to take during pregnancy?

The obstetrician may provide a list of medications to avoid for pregnant patients. In general, they recommend avoiding NSAIDs (nonsteroidal anti-inflammatory drugs) like ibuprofen (Advil), opioids, aspirin, and some skin and acne medications. Antidepressants are not usually on that list, but a medical provider will make that decision on a case-by-case basis. 

Does mirtazapine affect fertility?

There is no clinical evidence to support the idea that mirtazapine impacts fertility one way or the other. People taking it should talk to their medical providers if they become pregnant or want to become pregnant. 

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.

More about Mirtazapine


Written by

Fact Checked by