If you are pregnant, think you may be pregnant or plan to become pregnant, talk with your doctor before taking trazodone.

Taking trazodone is generally not recommended for pregnant and/or breastfeeding women, and the FDA only recommends it for pregnant women if and when their physician decides it is safe and its potential benefits outweigh its potential risks.

Can Trazodone cause birth defects?

The FDA reports potential risks trazodone may have to the developing baby. Before taking trazodone, it is critical to talk with your doctor if you are pregnant, plan to become pregnant or think you might be pregnant.

Can Trazodone cause a miscarriage?

The FDA states that trazodone should only be used during pregnancy “only if the potential benefit justifies the potential risk to the fetus.”

Trazodone, Labor and Delivery

Trazodone is generally not recommended for pregnant women.

Trazodone and Lactation

In rat studies, trazodone has been found in the milk of lactating rats. A 2018 study concluded that trazodone is present in human breast milk in small amounts and found no effects on growth or development in babies whose mothers breastfed them while taking trazodone. Physicians, however, must always determine if the benefits of taking trazodone while breastfeeding will outweigh the risks, and this will differ from person to person. The FDA cautions using trazodone while breastfeeding and recommends talking to your doctor about whether you will take the medication or breastfeed.

Trazodone and Fertility

Trazodone has no shown effect on the fertility of rats at trazodone doses up to 7.3 times the MRHD in adults on mg/m2 basis in adolescents. There is little to no data about trazodone’s effect on human fertility, so you should always consult with your doctor before taking this medication.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.


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