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Interactions may occur between Rexulti (brexpiprazole) and alcohol.

Side Effects

Alcohol can increase the nervous system side effects of Rexulti. In particular, drinking alcohol while taking Rexulti may make you feel more dizzy, drowsy, and can reduce your ability to concentrate. Because some people may already experience impairment in thinking and judgment when taking Rexulti, drinking alcohol can worsen these experiences.


Alcohol interacts with brexpiprazole by increasing the drug side effects that affect the nervous system. These side effects include dizziness, drowsiness, and difficulty concentrating.

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