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If you are pregnant, planning to become pregnant or are breastfeeding, talk to your doctor before taking prednisone. It is generally not advisable to take prednisone during pregnancy, as it can cause fetal harm in the first trimester, according to the FDA.

Is it ok to take prednisone while pregnant?

In some cases, taking prednisone is necessary, even for pregnant women, specifically those who live with an autoimmune disease or cancer. In these cases, your doctor may alter your dosage, duration or change your medication, due to the fact that ceasing medication could allow these diseases to further harm the mother or even the baby. Always consult your physician before taking prednisone while you are pregnant.

A 2018 study concluded pregnant women with rheumatoid arthritis who took higher doses of prednisone experienced shorter gestational length compared to those who took lower doses.

According to a 2017 study, assessing the risk of prednisone intake for pregnant women, along with dose and duration, must be “balanced with the necessity of treating underlying disease.” Always talk with your doctor before taking prednisone if you are pregnant, think you are pregnant or plan to become pregnant.


According to the FDA, prednisolone is secreted in human milk. You should first consult with your doctor before taking prednisone if you plan to breastfeed your baby. Your doctor will determine the safety of prescribing you prednisone during and after pregnancy and may prescribe you the lowest dose possible.

Does prednisone affect female fertility?

The FDA states prednisone “was not formally evaluated in fertility studies,” but clinical use of the drug has resulted in menstrual irregularities.

Disclaimer: this article does not constitute or replace medical advice. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. To see our full medical disclaimer, visit our Terms of Use page.

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