People who are pregnant or plan to become pregnant should talk to their doctors about Xolair and pregnancy. Experts need more research in order to determine if Xolair (omalizumab) can affect a developing fetus. Current evidence suggests that parents might transmit this drug to developing fetuses, since IgG antibodies can cross the placental barrier.
Xolair and Breastfeeding
More research is needed in order to determine if Xolair is able to pass into breast milk. No information is currently available on whether or not omalizumab is present in breast milk or if it has any effects on milk production. Those who are breastfeeding or who plan to breastfeed should discuss safety concerns about the use of this medication while nursing.
Are asthma medications safe during pregnancy?
Experts associate unmanaged asthma with higher risks of serious health problems, including preeclampsia, premature birth, restricted fetal growth, and an increased risk of needing a C-section. Taking medication to control asthma during pregnancy is therefore important. That said, there are concerns about using certain types of asthma medications during pregnancy. Those who are pregnant should talk to their doctor about the safety and potential risks of different types of asthma medications, including omalizumab.
What is category B in pregnancy?
The FDA’s Category B in pregnancy means that studies involving non-human animals did not show risks to fetuses. However, this category also indicates that there have not been any well-controlled studies involving human pregnancies, so risks to human fetuses are not currently known.